PentOS OI™ Putty

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IFU for PentOS OI Family

100% Allograft DBM Putty - PentOS OI™ Putty is made from 100% human bone without any additional diluent or carrier to diminish its osteoinductive properties.

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Brand: Citagenix

SKU: PENTOSPUTTY

Part Number: PENTOSPUTTY

Size

$263.95(Starting From)

PentOS OI™ Putty | Made from 100% human bone without any additional diluent or carrier to diminish its osteoinductive properties.

EVERY lot used to manufacture PentOS OI™ products is verified to be osteoinductive and histologically demonstrates all five elements of bone formation. Proven to form bone. Every time. It’s that simple!

Applications:

Periodontal defects
Implant site development
Coronal defects around immediate implants
Extraction site repair
Implant dehiscence defects
Sinus lift procedures
Moderate localized ridge defects

All PentOS OI™ allografts must demonstrate all five elements of bone formation before they are released for use.

1. New bone
New bone is the final step in the maturation of the product.

2. Bone marrow
The presence of bone marrow indicates the ability of the product to differentiate into osteoblasts, chondrocytes, cartilage and new bone.

3. Osteocytes
Osteocytes are derived from osteoblasts, or bone forming cells, and are essentially osteoblasts surrounded by the products they secreted.

4. Cartilage
Cartilage is replaced by bone during ossification in the higher vertebrates. It is indicative that the bone formation is forthcoming.

5. Chondrocyte
A Chondrocyte is a unique cell type in articular cartilage tissue and is essential for cartilage formation and functionality. It arises from mesenchymal stem cells.

Post sterilization in-vivo testing on each lot must demonstrate the presence of new bone, bone marrow, osteocytes, cartilage and chondrocytes within 28 days in an athymic rat model otherwise we don’t call it PentOS OI™.
In-vitro tests of PentOS OI™ have demonstrated native levels of BMP-2 up to 19 times the native levels in the control.

Overview
Features and Benefits
Availability

PentOS OI™ Putty | Made from 100% human bone without any additional diluent or carrier to diminish its osteoinductive properties.

Applications:

Periodontal defects
Implant site development
Coronal defects around immediate implants
Extraction site repair
Implant dehiscence defects
Sinus lift procedures
Moderate localized ridge defects

All PentOS OI™ allografts must demonstrate all five elements of bone formation before they are released for use.

1. New bone
New bone is the final step in the maturation of the product.

2. Bone marrow
The presence of bone marrow indicates the ability of the product to differentiate into osteoblasts, chondrocytes, cartilage and new bone.

3. Osteocytes
Osteocytes are derived from osteoblasts, or bone forming cells, and are essentially osteoblasts surrounded by the products they secreted.

4. Cartilage
Cartilage is replaced by bone during ossification in the higher vertebrates. It is indicative that the bone formation is forthcoming.

5. Chondrocyte
A Chondrocyte is a unique cell type in articular cartilage tissue and is essential for cartilage formation and functionality. It arises from mesenchymal stem cells.

PentOS OI™ Putty | Features & benefits

Verified to be osteoinductive
Osteoconductive
Excellent handling characteristics
Resists irrigation
Sterilized using low-dose gamma irradiation
Ready to use
Stored at room temperature

PentOS OI™ Putty is available in syringes of:

0.5 cc
1.0 cc
2.5 cc
5.0 cc

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